naturesQue Regeneration line
The essence of nature in expert hands
The naturesQue regenerative materials combine the strengths of the natural origin of the material with scientific and clinical expertise for tissue regeneration.
naturesQue regenerative materials
In the area of bone substitute materials, naturesQue has two products:
- an innovative xenohybrid bone substitute material derived from bovine bone, coated with a co-polymer mix and collagen fragments and
- an established xenogeneic bone substitute material derived from porcine cancellous bone
In the area of collagen products, naturesQue has three products:
- a stable porcine barrier membrane to protect the augmentation material,
- microfibrillar bovine collagen that forms a highly viscous gel after exudate uptake and has intrinsic hemostatic properties,
- a porcine collagen fleece that retains its 3D structure and stabilizes the blood clot
Xenogeneic collagen products
Collagen is highly conserved throughout evolution, meaning that xenogeneic collagen is very similar to that of humans and generally tolerated exceptionally well. Along with the donor species and the tissue used, there are a number of other factors that are critical for the properties of collagenous medical devices, with the procedures used during harvesting playing a role in which characteristics are highlighted in the product. Modern medicine is inconceivable without collagens and their use is one of many important therapeutic concepts.
Fibrillar collagens are proteins with a high tensile strength that are essential for structure formation and biomechanics in tissues. Collagen has positive effects in healing. In the early phases, it has intrinsic hemostatic properties while also being able to absorb large volumes of fluid, thus helping to create a moist wound environment that encourages healing [2].
| Properties of xenogeneic collagens | Function and use in regeneration |
|---|---|
| Conserved throughout evolution | Significant similarity between human and xenogeneic collagens leads to outstanding tolerance of xenogeneic collagens |
| Intrinsic hemostatic properties | collagen can act as a substrate for platelet binding[3] |
| Ability to integrate into the surrounding tissue | Thanks to the good tolerance of xenogeneic collagens, they are generally integrated into the surrounding tissue and broken down by physiological catabolic processes. |
| Adaptable properties resulting from the processing method | Tear-resistant fibrillar collagen can be processed to produce a number of sophisticated medical devices with different properties – including:
|
Universal solutions will never satisfy all requirements
For years we at BEGO Implant Systems have implemented the system concept in the area of implant dentistry. For this reason, BEGO Implant Systems works to-gether with partners in certain areas so that we are always able to offer products at the peak of dental technology. Our procedure in the area of regeneration materials is called OWN Brand Dis-tribution Label – an expression for us of partnerships that are full of synergies between manufacturers with established expertise in innovative regenerative biomaterials and our expertise as a developer, manufacturer, and distributor of dental implants. BEGO Implant Systems will stake out a stronger position in the area of regenera-tive materials in implant dentistry with the naturesQue product line because we perfectly combine the established with the innovative.
The framework conditions and rules of the game in the area of medical devices
Our naturesQue product line is synonymous with modern and successful regenerative materials. In light of increasing regulatory requirements, this is simply not enough. For BEGO Implant Systems and our partners this means that our approach and the implementation of regulatory frameworks have to be implemented conscientiously, precisely, reliably, and practicably.
- Haugen HJ, Lyngstadaas SP, Rossi F, Perale G. Bone grafts: which is the ideal biomaterial? J Clin Periodontol. (2019);46 Suppl 21:92-102
- Kujath P, Michelsen A. Wounds – From Physiology to Wound Dressing. Deutsches Ärzteblatt International Dtsch Arztebl Int (2008) 105;13: 239–48
- D. Rothamel, F. Schwarz, V. Stoldt, M. Herten, C. Kotthaus, J. Becker. In-vitro-Testung der Thrombozytenaggregation an zahnärztlich verwendeten kollagenen Hämostyptika. Mund- Kiefer- und Gesichtschirurgie 10(3):148-54 · May 2006